Electrical synapses interconnecting axons in the optic nerve head–a novel model of optic nerve function

A Novel Animal Model of Partial Optic Nerve Transection Established Using an Optic Nerve Quantitative Amputator

BACKGROUND Research into retinal ganglion cell (RGC) degeneration and neuroprotection after optic nerve injury has received considerable attention and the establishment of simple and effective animal models is of critical importance for future progress. METHODOLOGY/PRINCIPAL FINDINGS In the present study, the optic nerves of Wistar rats were semi-transected selectively with a novel optic nerv...

Effect of scuba-diving on optic nerve and sheath diameters

  Background :There is not any data available about the effect of high bar pressure condition on intracranial pressure. In this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   Methods : Twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. Only one perso...

Electrical potentials from the eye and optic nerve of Strombus: effects of electrical stimulation of the optic nerve.

1. Photic stimulation of the mature eye of Strombus can evoke in the optic nerve 'on' activity in numerous small afferent fibres and repetitive 'off' bursts of afferent impulses in a smaller number of larger fibres. 2. Synchronous invasion of the eye by electrically evoked impulses in small optic nerve fibres (apparently the 'on' afferents, antidromically activated) can evoke a burst of impulse...

P129: Use of Stem Cells to Regenerate Degenerative Optic Nerve

Stem cells are undifferentiated cells that have the ability to convert to different types of cells and after dividing, they can produce their own cells or other cells. Axons of the retinal ganglion cells, from the optic nerve. These cells lose the ability to regenerate themselves before birth. Optic nerve degeneration can result from various causes including increased intraocular pressure, comp...

Optic nerve ischemia: optic nerve sheath decompression alone or with optic nerve decompression.